Housed within the UNESCO-listed Grand Hôtel-Dieu—the city’s former hospital dating back to the Middle Ages—this 2019-renovated landmark brings 144 rooms and suites into a soaring 18th-century Soufflot-designed dome. Interiors by Jean-Philippe Nuel incorporate Lyon’s silk heritage. Highlights include the bar Le Dôme, the modern Epona restaurant, a 1,500 m² conference centre (L’Académie), and a Le Tigre Spa with hammam, sauna, gym, and yoga options.
